Browsing by Author "Koçyiğit, Ümit M."
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Biologically active phthalocyanine metal complexes: Preparation, evaluation of α-glycosidase and anticholinesterase enzyme inhibition activities, and molecular docking studies
Güzel, Emre; Koçyiğit, Ümit M.; Taslimi, Parham; Erkan, Sultan; Taskin, Omer S. (Wiley, mart 2021)In this study, preparation, as well as investigation of α-glycosidase and cholinesterase (ChE) enzyme inhibition activities of furan-2-ylmethoxy-substituted compounds 1–7, are reported. Peripherally, tetra-substituted ... -
Molecular hybrids integrated with imidazole and hydrazone structural motifs: Design, synthesis, biological evaluation, and molecular docking studies
Tapera, Michael; Kekeçmuhammed, Hüseyin; Sarıpınar,Emin; Doğan, Murat; Tüzün,Burak; Koçyiğit, Ümit M.; Çetin, Feyza Nur (elsevier, 03.10.2023)In the present work, a series of compounds containing imidazole and hydrazone structural frameworks were synthesized and characterized using various spectral techniques, including 1H NMR, 13C NMR, FTIR, and HRMS. Synthesized ... -
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
Gezegen, Hayreddin; Gürdere, Meliha B.; Dinçer, Ayşegül; Özbek, Oğuz; Koçyiğit, Ümit M.; Taslimi, Parham; Tüzün, Burak; Budak, Yakup; Ceylan, Mustafa (2021)A new class of cyanopyridine derivatives (10a-e and 11a-e) containing the phenylurea unit was synthesized and tested against some metabolic enzymes including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and ...